LL-37: What It Is and Its U.S. Regulatory Status

What is LL-37?

LL-37 is a naturally occurring human peptide made of 37 amino acids. Its name comes from the first two amino acids in its chain, both leucine (L), and its length. It is the only member of the cathelicidin family of antimicrobial peptides found in humans.

The body makes LL-37 by cutting it from a larger precursor protein called hCAP18. It is produced by immune cells and by cells lining the skin, airways and gut, and it is part of the innate immune system, the body’s first line of defense.

U.S. regulatory status

Current status: Not FDA-approved.

In practical terms, LL-37 has not gone through the FDA review that a drug must pass before it can be marketed for use in people. There is no FDA-approved product that contains it.

LL-37 is widely studied in laboratory research, but that research does not make it an approved medicine.

Why Peptide Labs does not sell LL-37

Peptide Labs does not sell this compound. This page is general information, not medical advice. We do not supply, prepare or distribute LL-37 in any form, and nothing on this page should be read as an offer.

If you have questions about LL-37 or a related health concern, talk to a licensed healthcare provider who knows your medical history.

Related reading

See the full list of compound profiles in the Peptide Guide.