Sermorelin: What It Is and Its U.S. Regulatory Status

What is sermorelin?

Sermorelin is a synthetic peptide made of the first 29 amino acids of growth hormone-releasing hormone (GHRH). This short section is the active part of the natural hormone, which the hypothalamus uses to signal the pituitary gland to release growth hormone. For that reason, sermorelin is classed as a GHRH analog.

Sermorelin acts one step earlier in the hormone chain than growth hormone itself. It is not growth hormone, and it is a different compound from newer GHRH analogs such as tesamorelin and CJC-1295.

U.S. regulatory status

Current status: FDA-approved prescription drug (Rx only).

This means the FDA has reviewed and approved at least one product containing sermorelin for specific uses, and it can only be dispensed with a valid prescription. The approval covers the approved product itself. It does not extend to unapproved products sold under the same name.

Brand name

Sermorelin was approved by the FDA under the brand name Geref. It was approved for use in certain children with growth hormone deficiency and as a diagnostic agent to test pituitary function. The manufacturer later discontinued the branded product.

How is it accessed?

As a prescription-only substance, sermorelin may only be obtained with a prescription from a licensed healthcare provider and dispensed by a licensed pharmacy. A provider will typically review lab results and medical history before deciding whether any hormone-related medicine is appropriate.

GHRH and its analogs, including sermorelin, are prohibited in competitive sport under the World Anti-Doping Code.

Why Peptide Labs does not sell sermorelin

Peptide Labs does not sell this compound. This page is general information, not medical advice. We are not a pharmacy, and we do not provide prescription medicines of any kind.

For personal medical questions, including questions about sermorelin, the right person to ask is a licensed healthcare provider.

Related reading

See the full list of compound profiles in the Peptide Guide.