SS-31 (Elamipretide): What It Is and Its U.S. Regulatory Status

What is SS-31?

SS-31, known by the generic name elamipretide, is a synthetic peptide made of four amino acids. It was designed to enter cells and concentrate in mitochondria, where it binds to cardiolipin, a fat molecule found in the inner mitochondrial membrane. The “SS” comes from the names of the two scientists who first described this family of peptides.

Elamipretide has been studied in clinical trials for Barth syndrome, a rare inherited condition that affects mitochondria, as well as in other mitochondrial disorders.

U.S. regulatory status

Current status: Rx only where approved – verify current FDA status.

The U.S. status of elamipretide should be verified directly with the FDA, because it has changed recently. Where it is approved, it is a prescription-only medicine intended for specific rare conditions, and it may only be dispensed with a valid prescription.

Why Peptide Labs does not sell SS-31

Peptide Labs does not sell this compound. This page is general information, not medical advice. Our Peptide Guide exists to explain what these compounds are and how they are regulated, not to supply them.

Anyone with questions about elamipretide should speak with a licensed healthcare provider, who can explain the current evidence and the legal status in plain terms.

Related reading

See the full list of compound profiles in the Peptide Guide.