Kisspeptin-10: What It Is and Its U.S. Regulatory Status

What is kisspeptin-10?

Kisspeptin-10 is a peptide made of ten amino acids. It is the shortest active fragment of kisspeptin, a family of natural peptides made from the KISS1 gene. Longer forms include kisspeptin-54, also called metastin.

The KISS1 gene was first identified in 1996 by researchers studying how cancer cells spread. It was named after the town of Hershey, Pennsylvania, home of the research center and of a well-known chocolate brand.

What does kisspeptin do in the body?

Kisspeptin acts on a receptor called KISS1R, also known as GPR54. Scientists now recognize kisspeptin as a key upstream signal for gonadotropin-releasing hormone (GnRH), which controls the release of the reproductive hormones LH and FSH. Differences in the kisspeptin system have been linked to problems with puberty.

Kisspeptin and its fragments have been studied in human research on reproductive hormones. This research is ongoing, and kisspeptin-10 has not been developed into an approved medicine.

U.S. regulatory status

Current status: Not FDA-approved.

In practical terms, kisspeptin-10 has not gone through the FDA review that a drug must pass before it can be marketed for use in people. There is no FDA-approved product that contains it.

Because it affects the hormone system that controls fertility, questions about kisspeptin belong with a licensed endocrinologist or reproductive specialist, not with online sources.

Why Peptide Labs does not sell kisspeptin-10

Peptide Labs does not sell this compound. This page is general information, not medical advice. We do not supply, prepare or distribute kisspeptin-10 in any form, and nothing on this page should be read as an offer.

If you have questions about kisspeptin-10 or a related health concern, talk to a licensed healthcare provider who knows your medical history.

Related reading

See the full list of compound profiles in the Peptide Guide.